Blossom Russo is a highly intelligent and spunky teenager. The youngest of three, she lives with her divorced musician father, Nick, eldest brother and recovering substance abuser Anthony, and decidedly not-so-bright middle brother Joey. Along for the ride is Blossom's ditzy best friend, Six, who sometimes shows flashes of great perception.
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Mayim Bialik
Blossom Russo
Joey Lawrence
Joey Russo
Michael Stoyanov
Anthony Russo
Jenna Von Oÿ
Six LeMuere
Ted Wass
Nick Russo
Finola Hughes
Carol Russo
Samaria Graham
Shelly Lewis Russo
Courtney Chase
Kennedy Russo